WormMine: ExpressionPattern Expr4688

• Primary Identifier: Expr4688
• Subcellular Localization: Intestinally expressed PGP-2::GFP was localized to prominent vesicular structures and the plasma membrane in embryos and adults. Similar organelles were stained by anti-PGP-2 antibodies. Anti-PGP-2 antibodies only stained intracellular compartments in embryos and adults, suggesting that the PGP-2::GFP might be partially mislocalized to the plasma membrane. PGP-2::GFP colocalized with birefringent material and the V-ATPase subunit FUS-1 in embryos, and in adults PGP-2::GFP colocalized with autofluorescent compartments. PGP-2 antibodies stained compartments containing GLO-1::GFP. These results indicate that PGP-2 and PGP-2::GFP are associated with the gut granule membrane.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003996	pgp-2	C34G6.4	Caenorhabditis elegans

0 Life Stages