WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Anatomy Term :

Definition  Ring motor neuron Name  RIMR
Primary Identifier  WBbt:0005053 Synonym  lineage name: ABprppaapap

1 Children

Definition Name Synonym Primary Identifier
nucleus of pedigree ABprppaapap ABprppaapap nucleus   WBbt:0002714

1 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Top 300 transcripts enriched in RIML, RIMR according to single cell RNAseq. Top 300 enriched transcripts were determined by log2.ratio of the tpm in the cell type vs the tpm in the other cells * the log2 of the cell.type tpm. WBPaper00061340:RIM

76 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
    Expr4381 Expressed in AVA, AVB, DVA, I5, RID, RIM, PVQ, SAA, SIA, SIB, SMB(?), SMD, ventral cord motor neurons, some unidentified neurons in the head. Also expressed head muscles (weak), body wall muscles (weak).  
    Expr4531 Expressed in RIML/R  
    Expr15649    
    Expr15442    
    Expr15558    
    Expr15571    
    Expr15572    
    Expr15573    
    Expr15579    
    Expr15586    
    Expr15651    
    Expr15652    
    Expr15589    
    Expr13158    
    Expr15591    
    Expr12196 To determine where lite-1 is expressed and identify likely sites of lite-1 function, the authors generated and examined worms carrying one of four transgenes derived from the wild-type lite-1 locus: a genomic fragment (lite-1 genomic), a transcriptional fusion (lite-1prom::gfp), a C-terminal translational fusion (lite-1prom::lite-1::gfp), and an N-terminal translational fusion (lite-1prom::gfp::lite-1). GFP expression was observed in a total of 29 cells: pharyngeal neurons M1, M4, M5, and MI; non-pharyngeal neurons ASK, ADL, ASI, ASH, AVG, AVB, RIM, ADF, PHA, PHB, and PVT; and non-neuronal cells Hyp3 (hypoderm), AMso (amphid socket cells), and PHso (phasmid socket cells). AVB was observed only with the C-terminal fusion transgene, and RIM and ADF were observed only with the transcriptional fusion transgene. lite-1 expression in AVG and PVT was previously reported.  
    Expr15598    
Picture: Fig 3.   Expr8850 Neuronal Expression: AVA, AVB, AVE, PVC, AIB, AUA, AVG, RIB, RIC, SAA, SIA, SIB, RIF, RIM, RMD, RME, SMD, DA, DB, VA, VB, M5, NSM, MC, I3, MI?. Non-neuronal Expression: rectal epithelium, body wall muscle, spermethecae, vulva muscle.  
    Expr15604    
    Expr15608    
    Expr11375 eat-4 is expressed in 78 of the 302 neurons of the adult hermaphrodite, which fall into 38 neuron classes (out of a total of 118 anatomically defined neuron classes in the hermaphrodite). Most of these neurons are either sensory- or interneurons. Only two motorneurons utilize glutamate; both are located in the pharynx.  
    Expr15611    
4.2 k   Expr15345    
4.2-1k   Expr15346    
Cells expressing TAX-6 were visualized using several tax-6::gfp fusion genes. The expression of tax-6 is under diverse transcriptional controls. Reporter gene fusion type not specified. pAK43 is a larger transgene that should include all promoter regions for tax-6 transcription, since another gene is encoded just upstream of this region and tax-6 mRNA does not seem to be derived from a polycistronic transcript.   Expr1824 When introduced into wildtype animals, pAK43 drove TAX-6 expression in many sensory neurons, as well as interneurons including AIY and AIZ, and most, if not all, muscle cells. pAK43 is expressed in muscle, AIB, AIY, AIZ, RIA, RIB, RIS, RIM, ASI, ADF, ASH, ASK, ADL, AUA, PHA, PHB, AVE. It is also expressed in AFD, ASE, AWA, AWC, AVK, AIM, RMDV, AVA.  
    Expr13711 GFP::UBR-1 exhibits strong expression in a fraction of neurons and all musculatures throughout development, and weak expression in hypodermal seam cells. In the motor circuit, UBR-1::GFP's expression is prominent in premotor interneurons (INs) of the reversal motor circuit, and is absent from all ventral cord motor neurons that execute locomotion. Robust expression of UBR-1 was present at the pharynx; neuronal UBR-1::GFP signals were present in the AVA, AVE and RIM premotor interneurons, and other unidentified neurons.  
    Expr13712 GOT-1::GFP exhibited cytoplasmic expression in all somatic tissues, including broad expression in the nervous system. Robust expression of GOT-1 was present at the pharynx; neuronal UBR-1::GFP and GOT-1::GFP signals were present in the AVA, AVE and RIM premotor interneurons, and other unidentified neurons.  
    Expr16053 A functional transcriptional reporter for CKR-1 revealed strong expression in many neurons and weak expression in the intestine. In the nervous system, ckr-1 expresses in the head and ventral cord neurons. CKR-1-expressing neurons include head motor neurons SMD and RME , interneurons AIB and RIM, peptidergic neurons RIS, and body motor neurons A, B, and D.  
    Expr16493 By characterizing the expression patterns of alh-9, alh- 11, and chdh-1 transgenic reporters, we identified expression of all three putative biosynthesis pathway genes in neurons. In particular, the RIM neurons showed expression of both chdh-1 and alh-11, indicating that these neurons have the capacity to synthesize betaine from choline.  
    Expr15194 We consistently observed aat-1::mCherry fluorescence in several pairs of head neurons; pharynx; reproductive system -including vulval muscles, uterine muscles, and uterine-vulva cells; excretory cells; and weak transgene expression in the intestine of adult animals. Reporter fusions controlled by the aat-1 and nkat-1 promoters showed overlapping expression patterns in RMDV and RIM neurons  

11 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching. embryo Ce WBls:0000003
  The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo. fully-elongated embryo Ce WBls:0000021
  The C. elegans life stage spanning 350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation until elongation is over. elongating embryo Ce WBls:0000015
  The C. elegans life stage spanning 290-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage when embryo just finished gastrulation and is enclosing. enclosing embryo Ce WBls:0000013
  The C. elegans life stage spanning 0-350min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 560 cells. From start of first cleavage until cleavage is over. proliferating embryo Ce WBls:0000004
  The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage. 3-fold embryo Ce WBls:0000020
  The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo. 1.5-fold embryo Ce WBls:0000018
  The C. elegans life stage spanning 390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo. comma embryo Ce WBls:0000017
  The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo. 2-fold embryo Ce WBls:0000019
  The C. elegans life stage spanning 350-390min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. Emrbyo elongation started but have not formed comma shape yet. The shape of embryo looks like a lima bean. A stage right before comma embryo. Also called lima embryo or lima bean stage. bean embryo Ce WBls:0000016
  The C. elegans life stage spanning 210-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage before the fast cleavage of cells finishes. late cleavage stage embryo Ce WBls:0000014

4 Parents

Definition Name Synonym Primary Identifier
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
embryonic cell ABprppaapa   WBbt:0006079
Neuron class of two interneuron motoneurons that innervate muscles in the head via NMJs in the nerve ring. RIM   WBbt:0005835
neuron type, cell body located in right lateral ganglion. lateral ganglion right neuron   WBbt:0005100