WormMine: AnatomyTerm WBbt:0006994

• Definition: cell, which is the anterior descendent of TL.
• Name: TL.a
• Primary Identifier: WBbt:0006994

7 Children

Definition	Name	Synonym	Primary Identifier
cell, which is the posterior descendent of TL.a.	TL.ap		WBbt:0007010
Anterior daughter cell of TL.a, fuses into postembryonic large hypodermal syncytium.	TL.aa		WBbt:0006998
hyp7 syncytium in male.	hyp7 syncytium male		WBbt:0008070
nucleus of pedigree TL.a	TL.a nucleus		WBbt:0002857
Anterior daughter cell of TL.a, fuses into postembryonic large hypodermal syncytium in hermaphrodite.	TL.aa hermaphrodite	lineage name: TL.aa	WBbt:0004228
hyp7 syncytium in hermaphrodite.	hyp7 syncytium hermaphrodite		WBbt:0008071
Anterior daughter cell of TL.a, fuses into postembryonic large hypodermal syncytium in male.	TL.aa male	lineage name: TL.aa	WBbt:0004181

0 Expression Clusters

7 Expression Patterns

• Primary Identifier: Expr4287
• Pattern: psa-3 was expressed in the T cell, head neurons, posterior gut cells, hypodermal cells (hyp7, hyp9, and hyp10), and P blast cells. Of the seam cells, only the T cell expressed psa-3. During mitosis of the T cell, the PSA-3 protein was uniformly distributed in the T cell. Soon after the T cell division (before V6 cell division, which occurs about 30 min after T cell division), the psa-3 expression in the two daughter cells was almost the same. In the later stage, after V6 cell division, the psa-3 expression in T.a had decreased and that in T.p increased. After the next round of divisions, the psa-3 expression had greatly increased in the posterior (T.pa and T.pp), but not the anterior, granddaughters.

• Primary Identifier: Expr4251
• Remark: mhIs9 rescued the lin-17 T and B cell polarity defects.
• Pattern: mhIs9 males contain a lin-17::gfp construct that was expressed in the membranes of the T, B cells and their descendants as well as the F, P11, P12 and vuval precursor cells.
• Subcellular Localization: membrane

• Primary Identifier: Expr12036
• Pattern: mom-2 expression was observed in the male blast cells B, F, Y as well as P12.p, T.a, T.p, hyp7, hyp8 and hyp10 in syEx664 males.

• Primary Identifier: Expr2550
• Reporter Gene: This construct rescued the tcl-2 T cell and gonad defects, but only partially rescued the Pv1 defects.
• Pattern: tcl-2::gfp is expressed strongly in the cytoplasm of the pharynx muscle cells and several head neurons, probably the IL1s or IL2s, throughout development. Several other unidentified neurons in the tail region expressed GFP throughout development. Although tcl-2 mutants display gonad, and P12.p cell fate defects, GFP expression was not observed in these cells or their descendants in L1 animals.
• Subcellular Localization: In contrast to the cytoplasmic expression in head neurons, weak GFP expression was observed in the nuclei of the T cells and the T cell daughters, T.a and T.p. The level of GFP expression was equal in both T cell daughters.

• Primary Identifier: Expr11089
• Pattern: ceh-20 was expressed in nearly all of the cells, including the T cell. During T cell mitosis, CEH-20 was distributed uniformly. Soon after T cell division (before V6 division), the nuclear level of CEH-20 was equal in the daughter cells, while in the late stage, after V6 division, the nuclear level in T.a was slightly greater and that in T.p was slightly less, resulting in the differential subcellular localization of CEH-20 between the daughter cells (8/33 animals showed the asymmetric localization; i.e., strong nuclear localization in T.a and weak nuclear and cytoplasmic localization in T.p).

• Primary Identifier: Expr3488
• Pattern: Expressed in most cells during embryogenesis and in many if not all cells in developing larvae. Expressed in the T cell and the T-cell daughters. GFP fluorescence was observed in both of the daughter nuclei, indicating that there was no asymmetry in the expression pattern of let-19 during T-cell division.

• Primary Identifier: Expr3489
• Pattern: Expressed in most cells during embryogenesis and in many if not all cells in developing larvae. Expressed in the T cell and the T-cell daughters. GFP fluorescence was observed in both of the daughter nuclei, indicating that there was no asymmetry in the expression pattern of dpy-22 during T-cell division.

0 Life Stages

2 Parents

Definition	Name	Synonym	Primary Identifier
Tail seam hypodermal cell, postembryonic blast cell, functions as phasmid socket in L1	TL	lineage name: ABplappppp	WBbt:0004946
a cell that is born in a worm after hatching.	post-embryonic cell		WBbt:0007030