WormMine: ExpressionPattern Expr10630

• Pattern: The expression of this ZYX-1-GFP protein was observed in spermatheca, body wall muscles as well as neurons. The expression was confirmed with anti ZYX antibodies but the signal was weaker.
• Primary Identifier: Expr10630
• Subcellular Localization: The ZYX-1-GFP protein was detected at dense bodies and M-lines, as well as in the nucleus of body wall muscle cells, and in both cell bodies and axons of neurons. The ZYX- 1-GFP protein mainly localized in the middle region of dense bodies and partially overlaps with the ATN-1 and the DEB-1 containing regions.Immunoelectron microscopy experiments on transgenic zyx-1::gfp expressing worms showed a localization of the ZYX-1-GFP protein at dense bodies, over the whole length of M-lines, and in the nucleus. FRAP experiments indicate that ZYX-1 is a highly dynamic protein within the muscle cell and may shuttle between muscle adhesion complexes and the nucleus.

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
an accordion-like tube that contains sperm and is the site of oocyte fertilization.	spermatheca		WBbt:0005319
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006999	zyx-1	F42G4.3	Caenorhabditis elegans

0 Life Stages