1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00000481 | cha-1 | ZC416.8 | Caenorhabditis elegans |
| Primary Identifier | Expr7819 | Remark | Picture: Figs. 3, 4. The three different patterns of subcellular staining of ChAT (smooth with R388; punctate with MAbs1402/1414; mixed with MAbs1401/1415/1432) all appear to be specific: they were found in the same cells in the body and tail, showed decreased staining in specific cha-1 mutants, and showed increased staining in transgenic strains containing extra copies of the cha-1 and unc-17 genes. |
| Subcellular Localization | With monoclonal antibodies 1402 and 1414, immunoreactivity was largely present in synaptic regions and was very similar to staining with anti-VAChT antibodies. With the three other monoclonal antibodies (MAbs 1401, 1415, 1432), staining included both punctate regions associated with synapses and smoother areas of staining in somas and processes; this staining appeared to be cytosolic or associated with the plasma membrane and other membranes. In addition, distributed punctate anti-ChAT staining was occasionally detected in nonneuronal tissues (presumably hypodermis and/or muscle) in the head. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00000481 | cha-1 | ZC416.8 | Caenorhabditis elegans |
