|
|
Expr2733
|
UNC-45 function. In this transgenic line, GFP expression is detected in all muscle cells examined, including body wall muscle cells, pharyngeal muscle cells, anal-intestinal muscle cells, gonad sheath muscle cells, and sex-specific muscle cells in both males and hermaphrodites. This supports a general role of UNC-45 in development and function of all muscles. |
The GFP expression pattern resembles the pattern of A-bands of thick filaments. To confirm this, the same field was examined under polarized light microscopy and an identical pattern was seen. This indicates that functional UNC-45::GFP is associated with thick filaments in body wall muscles. |