| Primary Identifier | Expr8817 | Remark | Picture: Figure 2. |
| Subcellular Localization | CDE-1 was detected throughout the female germline cytoplasm, where it was enriched in the perinuclear region. However, CDE-1 did not display the clear granular structure that is commonly observed for the P granule marker, PGL-1 at this stage. In the sperm-producing germlines of both males and L4 stage hermaphrodites, bright granules were found in close proximity to the condensing DNA of maturating sperm. In embryos, CDE-1 was detected in perinuclear granules in the P-cell lineage, mainly colocalizing with PGL-1. In addition, staining could be detected on the outer edges of condensing chromosomes at prometaphase. This staining became more intense on the spindle-facing sides of the metaphase plate and remained detectable through anaphase. Parallel experiments in cde-1 mutant animals did not show the patterns described above, indicating that the observed signals reflect true CDE-1 localization. Specific intestinal staining as previously reported based on a transgenic approach (see Expr3928) could not be detected. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. | germ line | germline | WBbt:0005784 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00019629 | cid-1 | K10D2.3 | Caenorhabditis elegans |
