WormMine: ExpressionPattern Expr12120

• Pattern: Transgenic animals showed expression of GFP::FZR-1 in many somatic cells during larval development, at levels that varied in a cell type- and developmental stage-dependent manner. Initiation of cell cycle entry during larval development coincided with a substantial increase in nuclear GFP::FZR-1 (observed in ventral cord precursor cells, vulval precursor cells, intestinal cells and seam cells).
• Primary Identifier: Expr12120
• Subcellular Localization: Initiation of cell cycle entry during larval development coincided with a substantial increase in nuclear GFP::FZR-1 (observed in ventral cord precursor cells, vulval precursor cells, intestinal cells and seam cells). GFP::FZR-1 levels are high in actively cycling cells and decrease in cells arrested in G0/G1.

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
cell that has the potential to form structural part of a vulva.	vulval precursor cell	VPC	WBbt:0007809
any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm.	intestinal cell		WBbt:0005792
Blast cell lying ventrolaterally in the late embryo and L1 larval stage which divides during the late L1 larva in stereotypical reiterated fashion to give rise to many motor neurons which begin function in the ventral cord and preanal ganglion of the early L2 larva, as well as hypodermal cells (which fuse into hyp7) and a series of programmed cell deaths. In addition, the Pn.p daughters of P3 through P8 lineages persist without fusing into the hyp7 syncytium until mid L3 stage when they can be induced to divide further to produce vulval epithelial cells (vulA - vulF) or more hyp7 cells. P0 is also known as W.	ventral cord blast cell	P cell	WBbt:0008115

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001510	fzr-1	ZK1307.6	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023