WormMine: AnatomyTerm WBbt:0005744

• Name: reproductive tract
• Primary Identifier: WBbt:0005744

1 Children

Definition	Name	Synonym	Primary Identifier
organ producing either sperm or ova.	gonad		WBbt:0005175

2 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Proteins that are enriched in productive tract of adult female Brugia malayi.	Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction.	WBPaper00048706:productive-tract_enriched
	Proteins that are only expressed in productive tract of adult female Brugia malayi.	Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction.	WBPaper00048706:productive-tract_only

3 Expression Patterns

• Primary Identifier: Expr1200036
• Pattern: Data from the TransgeneOme project

• Primary Identifier: Expr1200068
• Pattern: Data from the TransgeneOme project

• Primary Identifier: Expr14584
• Pattern: In hermaphrodites, swm-1 was expressed in posterior body wall muscle consistent with the non-sex-specific nature of this tissue. SWM-1::mCherry protein was detectable in muscle and secreted into the body cavity, as evidenced by its presence in coelomocytes. Interestingly, swm-1 also was expressed in the spermathecae, structures that are unique to the hermaphrodite gonad, and SWM-1::mCherry surrounded sperm that were stored in the spermathecal lumen. Indeed, SWM-1::mCherry protein was present throughout the outer hermaphrodite reproductive tract and it surrounded fertilized eggs. As it can be difficult to distinguish between the body cavity and the uterus, we used GFP-labeled seminal fluid to mark the lumen of the uterus. jn62[swm-1::mCherry] hermaphrodites mated to males that expressed TRY-5::GFP showed clear colocalization of SWM-1::mCherry and TRY-5::GFP in the uterus. In similar experiments, we found that muscle-derived SWM- 1::mCherry also colocalized with GFP transferred in seminal fluid. Thus, as in males, SWM-1 is secreted into the hermaphrodite body cavity and then taken up into the gonad, in which it is present throughout the sperm migratory path.

0 Life Stages

1 Parents

Definition	Name	Synonym	Primary Identifier
region of the body by which tissues, cells or cell parts are classified	body region		WBbt:0005738