WormMine: AnatomyTerm WBbt:0005009

• Definition: Ring motor neuron/interneuron
• Name: RMHR
• Primary Identifier: WBbt:0005009
• Synonym: lineage name: G1.r

1 Children

Definition	Name	Synonym	Primary Identifier
nucleus of pedigree G1.r	G1.r nucleus		WBbt:0002736

0 Expression Clusters

31 Expression Patterns

• Primary Identifier: Expr15649

• Primary Identifier: Expr15558

• Primary Identifier: Expr15571

• Primary Identifier: Expr15572

• Primary Identifier: Expr15573

• Primary Identifier: Expr15579

• Primary Identifier: Expr15586

• Primary Identifier: Expr15651

• Primary Identifier: Expr15652

• Primary Identifier: Expr15589

• Primary Identifier: Expr13158

• Primary Identifier: Expr15591

• Primary Identifier: Expr15598

• Primary Identifier: Expr15604

• Primary Identifier: Expr15608

• Primary Identifier: Expr15611

• Primary Identifier: Expr15351

• Primary Identifier: Expr15364

• Primary Identifier: Expr12716

• Primary Identifier: Expr12717

• Primary Identifier: Expr15624

• Primary Identifier: Expr16145
• Pattern: We found that in the adult nervous system unc-42 is strongly and consistently expressed in 40 neurons located in the head of the worm that fall into 15 anatomically distinct neuron classes. At the first larval stage, expression is detected in the same set of neuron classes as observed in the adult, with the addition of very weak and inconsistent expression in AVJ and SIA that disappears by the adult stage. In the embryo, expression is first observed in a few neuroblasts before the bean stage. At the bean stage, when most neurons have terminally divided, unc-42 expression commences and reaches the full complement of unc-42(+) cells at the 1.5-fold stage. The cellular sites of expression in the embryonic nervous system appear to be the same as observed post-embryonically, a notion further supported by recent scRNA data (Packer et al., 2019). No expression is observed outside the nervous system.

• Primary Identifier: Expr15658

• Primary Identifier: Expr15336

• Primary Identifier: Expr13957
• Pattern: Using a fosmid-based GFP translational fusion, we found that zag-1 was expressed in the six TRNs but not in the FLP and PVD neurons. In addition to TRNs, zag-1 was expressed in the AIB, AIM, AIN, AIZ, AVA, AVB, AVD, AVE, AVG, AVK, AVL, M4, M5, RIA, RIB, RIF, RIG, RIM, RIV, RMD, RME, RMF, RMH, SIA, and SMD neurons in the head, all the DD, VD, and VC neurons in the ventral cord, and the DVA, DVB, LUA, PDA, PVC, PVP, PVQ, PVR, and PVT neurons in the tail. zag-1 is also expressed in the serotonergic HSN neurons.

• Primary Identifier: Expr15854
• Pattern: lgc-54 was expressed in two neuron pairs: AVE and RMH.

• Primary Identifier: Expr15581

• Primary Identifier: Expr3177
• Pattern: Expressed in intestine, RMF, RMH.

• Primary Identifier: Expr12603
• Pattern: sem-2 expression was identified in several early blastomeres and in some neuronal and non-neuronal progenitors. Its expression colocalized with that of sox-2 in a few progenitors. As in vertebrates, sem-2 expression was observed in postmitotic neurons, but in contrast to the broad expression of SoxC genes in vertebrate postmitotic neurons, only a single class of postembryonic neurons expresses sem-2, the RMH class. sem-2 expression in these neurons is observed throughout larval and adult stages. We did not detect any sem-2 expression in the RME neurons themselves, but sem-2 is instead expressed in the progenitor of RMEL/R.

• Primary Identifier: Expr11638
• Pattern: As predicted from expression driven by the individual promoters, only 3 pairs of ring motorneurons (RMHs, RMFs, RMDs) expressed both ser-1::yfp and mpz-1::cfp. Unfortunately, attempts to colocalize the full length proteins were unsuccessful using this approach as SER-1::YFP and SER-1::CFP aggregated significantly when expressed in vulval muscle.

0 Life Stages

4 Parents

Definition	Name	Synonym	Primary Identifier
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
ventral ganglion, anterior part.	ventral ganglion (ant)		WBbt:0005266
Postembryonic blast cell, excretory socket in embryo	G1	lineage name: ABprpaaaapa	WBbt:0004780
Neuron class of two motoneurons which innervate muscles in the head via NMJs in the nerve ring.	RMH		WBbt:0006843