23 Children
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| A blast cell from which a neuron develops. | neuroblast | WBbt:0008594 | |
| cell that has the potential to form structural part of a vulva. | vulval precursor cell | VPC | WBbt:0007809 |
| Rectal cell, postembryonic blast cell in male | B cell | lineage name: ABprppppapa | WBbt:0003825 |
| Rectal cell, blast cell in male | F cell | lineage name: ABplppppapp | WBbt:0004799 |
| Postembryonic mesoblast of pedigree MSapaapp. | M cell | lineage name: MSapaapp | WBbt:0004489 |
| Rectal cell, postembryonic blast cell in male | U cell | lineage name: ABplppppapa | WBbt:0004942 |
| Rectal cell, postembryonic blast cell | K cell | lineage name: ABplpapppaa | WBbt:0004499 |
| Ventral Uterine precursor cell. | ventral uterine precursor | VU | WBbt:0006780 |
| Dorsal Uterine precursor cell. | dorsal uterine precursor | DU | WBbt:0006781 |
| any of two cells that generate all somatic tissues of the gonad proper (i.e. ovary or testis ) and genital ducts (e.g. uterus, vas deferens). | somatic gonad precursor | SGP | WBbt:0007854 |
| Rectal cell at hatching, becomes PDA in hermaphrodite, postembryonic blast cell in male | Y cell | lineage name: ABprpppaaaa | WBbt:0004578 |
| Blast cell which divides to product sex-specific muscle cells. | sex myoblast | WBbt:0008373 | |
| any of six ventral uterine intermediate precursor cells that are adjacent to the anchor cell and whose progeny are fated to become uv1 and utse cells. | uterine pi cell | WBbt:0007813 | |
| Tail lateral ectoblasts that give rise to neurons, hypodermis and glial lineages. While initially identical, after the L2 lethargus the T cell lineages become markedly different between males and hermaphrodites helping to provide the sexually dimorphic tail structures found in males. | tail precursor cell | T cell | WBbt:0008409 |
| Postembryonic neuroblast, analogous to Pn.a cells, also known as P0. | W cell | lineage name: ABprapaapa | WBbt:0004583 |
| Blast cell lying ventrolaterally in the late embryo and L1 larval stage which divides during the late L1 larva in stereotypical reiterated fashion to give rise to many motor neurons which begin function in the ventral cord and preanal ganglion of the early L2 larva, as well as hypodermal cells (which fuse into hyp7) and a series of programmed cell deaths. In addition, the Pn.p daughters of P3 through P8 lineages persist without fusing into the hyp7 syncytium until mid L3 stage when they can be induced to divide further to produce vulval epithelial cells (vulA - vulF) or more hyp7 cells. P0 is also known as W. | ventral cord blast cell | P cell | WBbt:0008115 |
| blast cell that divides to become mostly vas deferens cells (and a few seminal vesicle cells). | vas deferens precursor | WBbt:0008357 | |
| One of a pair of lateral neuroblasts that migrate separately within the body cavity during larval stages to produce a variety of cell types. | Q cell | WBbt:0008598 | |
| Ventrolateral ectoblast of the body that gives rise to neurons, hypodermis and seam cells. | V cell | WBbt:0008597 | |
| Head lateral ectoblast which gives rise to hypodermal cells in the head. | H cell | WBbt:0008596 | |
| Precursor cell of the male sensory ray (R1-R9). | ray precursor cell | WBbt:0006931 | |
| Ventral ganglion neuroblasts present at hatching, located near the excretory pore. | G cell | WBbt:0008599 | |
| any of six ventral uterine intermediate precursor cells that are not directly adjacent to the anchor cell and whose progeny are fated to become uterine cells other than uv1 and utse cells. | uterine rho cell | WBbt:0007814 |
4 Expression Patterns
| Remark | Reporter Gene | Primary Identifier | Pattern | Subcellular Localization |
|---|---|---|---|---|
| Expr12443 | A GFP fusion gene with 7.7 kb of nsy-4 upstream sequence was expressed beginning at the comma stage of embryogenesis and continuing until the adult. At the 2-fold stage of embryogenesis, expression was prominent in the excretory cell and in anterior epidermal cells. At the first larval stage, the nsy-4 reporter transgene was expressed in the excretory cell, in epidermal cells in the head (some or all of hyp 1-6) and tail (some or all of hyp 8-11), and in the P neuro-epidermoblasts, both before and after their ventral migration. Weak nsy-4::GFP expression was detectable in a few neurons. In three appropriate mosaic animals identified at the L1/L2 stage, nsy-4::GFP was observed in the AWC cell body. Expression was not detectable in AWC in older animals. | |||
| Expr9680 | Animals transgenic for a chromosomally integrated array of either madd-4Bp::YFP or madd-4Bp::RFP (called trIs79 and trIs80, respectively) expressed fluorescent protein in all commissural motor neurons and in no other cell types within the body (as opposed to the head). Through a mosaic analysis of animals harboring an extrachromosomal array of madd-4Bp::YFP, we found that the madd-4B promoter also drives expression in the head neurons RIA, RIC, lateral IL1s, lateral IL2s, OLLs, RMEs, and SABs. YFP may also be expressed in AVH, AVKL, and ASG, and AIZ. We also observed madd-4B-driven YFP expression during embryogenesis in the blast cells and corresponding terminally differentiated ventral cord motor neurons and head neurons. MADD-4B::YFP (trIs57) is localized to both the ventral and dorsal nerve cords. | |||
| Expr12833 | The LIN-23 protein is present both in all blast cells of embryos and in the wild-type germline. LIN-23 is present in the germline from the tip of the distal arm to the maturing oocytes. Its abundance seems relatively similar between the distal and proximal zones; however, its localization is concentrated within cytosol and is relatively excluded from nuclei. The distal region of the gonad is a syncytial tube with the germline nuclei packed around the outside with a hollow core. We find that LIN-23 is concentrated throughout the core and in the cytosolic spaces between the nuclei and is either absent from, or present at a much reduced level, in the nuclei themselves. Within developing oocytes in the proximal region of the gonad, it is also more abundant in the cytoplasm than nuclei. An interesting observation was the differential localization of LIN-23 in the cells of the early embryo. It is generally distributed throughout the cytosol, but its localization is dynamic being differentially excluded from the nucleus for much of the cell cycle, but a fraction of it accumulates to the nuclear compartment late in the cycle shortly before cell division. In the embryos shown, the nuclear compartment accumulation of LIN-23 is seen in a late AB blastomere but is absent in a slightly younger AB blastomere. Similarly, it can be seen in both the ABa and ABp blastomeres but absent from the nuclei of the EMS and P2 blastomeres. Because the ABa and ABp blastomeres divide slightly earlier than EMS and P2, they are inevitably later in the cell cycle. However, this pattern is not lineage dependent. | |||
| Expr12603 | sem-2 expression was identified in several early blastomeres and in some neuronal and non-neuronal progenitors. Its expression colocalized with that of sox-2 in a few progenitors. As in vertebrates, sem-2 expression was observed in postmitotic neurons, but in contrast to the broad expression of SoxC genes in vertebrate postmitotic neurons, only a single class of postembryonic neurons expresses sem-2, the RMH class. sem-2 expression in these neurons is observed throughout larval and adult stages. We did not detect any sem-2 expression in the RME neurons themselves, but sem-2 is instead expressed in the progenitor of RMEL/R. |
1 Parents
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| a cellular object that consists of subcellular components, expresses genes or functions. | Cell | Cell type | WBbt:0004017 |
