Staining of DNC-1 in one-cell and two-cell embryos revealed a striking accumulation at the cell-division remnant (also known as the residual body or midbody).
Primary Identifier
Expr1254
Remark
No detailed description on cellular expression pattern of later developmental stages.
Subcellular Localization
Centrosomal and kinetochore staining was also seen. In addition, cytoplasmic staining was seen. Initially, the accumulation of DNC-1 at cell-division remnants appeared upon completion of the first meiosis during polar-body formation. This spot persisted until the end of the first mitosis. DNC-1 appeared at the leading edge of the cleavage furrow of one-cell stage embryos, and persisted at the cell-division remnant until the end of the two-cell stage.
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