WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  All three gamete types of C. elegans (oocyte, male spermatocyte, and hermaphrodite spermatocyte) show meiosis-specific expression of HIM-3. No protein could be detected in somatic nuclei at any stage of development or in the distal tip nuclei that are undergoing mitotic divisions. A strong signal first appears in the transition zone where HIM-3 is associated with the chromatin of early meiotic prophase nuclei. Localization of HIM-3 becomes more discrete in pachytene and diplotene as the chromosomes synapse and desynapse. The protein remains associated with the chromosomes of oocytes at diakinesis; however, it could no longer be detected in postmeiotic sperm. The antibody identifies the first nuclei that are entering the pachytene stage of meiosis but does not stain the mitotic nuclei. Primary Identifier  Expr1163
Subcellular Localization  Nuclei. The him-3 protein localizes to the chromosome core and associates with both unsynapsed and synapsed chromosomes.
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2 Anatomy Terms

Definition Name Synonym Primary Identifier
a female haploid germ cell. oocyte ovum WBbt:0006797
A cell which gives rise to spermatids by meiosis. spermatocyte   WBbt:0006799

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001862 him-3 ZK381.1 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035