WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Anatomy Term :

Definition  cell, anterior descendent of Z4. Name  Z4.a
Primary Identifier  WBbt:0007025

3 Children

Definition Name Synonym Primary Identifier
post-embryonic cell of pedigree Z4.ap Z4.ap   WBbt:0007756
post-embryonic cell of pedigree Z4.aa Z4.aa   WBbt:0007687
nucleus of pedigree Z4.a Z4.a nucleus   WBbt:0003463

2 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Genes that are enriched in hermaphrodite Z1 and Z4 daughter cells according to RNAseq analysis towards FACS sorted Z1 and Z4 daughter cells. Cuffdiff v2.1.1 WBPaper00048690:hermaphrodite-Z1-Z4-daughter_enriched
  Genes that are enriched in male Z1 and Z4 daughter cells according to RNAseq analysis towards FACS sorted Z1 and Z4 daughter cells. Cuffdiff v2.1.1 WBPaper00048690:male-Z1-Z4-daughter_enriched

3 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
Expression pattern at adult stage was not described.   Expr1410 Expression in Z1 and Z4, the somatic gonad precursors, starts a few hours after these are born. Up to the formation of the somatic gonad primordium in late L2, LIN-26 protein was detected in all cells of the somatic gonad, except in the distal tip cells or dtcs (Z1.aa and Z4.pp). Staining was strongest in Z1 and Z4 and became weaker after each cell division. However, after Z1.a and Z4.p divided, LIN-26 was initially not detected in any of their daughters, but resynthesis occurred in Z1.ap and Z4.pa. During the L3 stage, expression was only detected in the anchor cell (AC) until the Pn.pxx cells were generated. After the last division round in L4 larvae, all uterine nuclei and two spermathecal-uterine junction nuclei expressed LIN-26 at very low levels. nuclei
    Expr3976 The NHR-25 protein can be detected in the nuclei of Z1 and Z4 as well as in the nuclei of their daughter cells, but not in the Z2 and Z3 precursors of the germline. nuclei
    Expr12127 In wild-type worms, POP-1::GFP expression was stronger in the nuclei of Z1.p and Z4.a cells than in Z1.a and Z4.p cells  

0 Life Stages

2 Parents

Definition Name Synonym Primary Identifier
Somatic gonad precursor cell Z4 lineage name: MSappaap WBbt:0004574
a cell that is born in a worm after hatching. post-embryonic cell   WBbt:0007030