WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Cluster :

Algorithm  For selection of DEGs, an unpaired t -test was performed followed by a significance analysis of microarray (SAM) test including a calculation that estimates the false discovery rate (FDR). FDR, reducing on the one hand type I errors for null associations, was set to a non-stringent level of <12.5%, mainly to guard from an increase of type II error and also based on findings by Levine et al. (2011), which described 12.5% as most acceptable optimum level of FDR, representing the 90th percentile of the normal distribution curve. DEGs exceeding a fold change of 1.25 were further analyzed with respect to their functional clustering. This fold-cut-off was chosen to allow an interpretation that is biologically meaningful, akin to the notion that data of sound technical and experimental quality which returns strong, statistically significant, absolute signal intensities is sufficiently robust to justify a fold-cut-off of >1.2. This analysis was conducted using the functional annotation clustering tool of the Database for Annotation, Visualization, and Integrated Discovery (DAVID; Huang et al., 2007). Description  Gene significantly down-regulated by treatment with 2.0mM of HuminFeed Hydroquinone until young adult stage (3 days), with a minimum fold change in gene expression of 0.8.
Primary Identifier  WBPaper00041002:HQ_3d_2.0mM_Down Regulated By Treatment  Treatment with 2.0mM of HuminFeed Hydroquinone until young adult stage (3 days).

0 Anatomy Terms

675 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000074 adm-2 C04A11.4 Caenorhabditis elegans
WBGene00000075 adm-4 ZK154.7 Caenorhabditis elegans
WBGene00000083 adt-2 F08C6.1 Caenorhabditis elegans
WBGene00000115 alh-9 F01F1.6 Caenorhabditis elegans
WBGene00000123 ama-1 F36A4.7 Caenorhabditis elegans
WBGene00000133 amt-1 C05E11.4 Caenorhabditis elegans
WBGene00000158 apg-1 Y105E8A.9 Caenorhabditis elegans
WBGene00000160 apb-1 Y71H2B.10 Caenorhabditis elegans
WBGene00000162 apd-3 W09G10.4 Caenorhabditis elegans
WBGene00000186 ark-1 C01C7.1 Caenorhabditis elegans
WBGene00000196 aars-1 W02B12.6 Caenorhabditis elegans
WBGene00000222 atf-6 F45E6.2 Caenorhabditis elegans
WBGene00000225 atgp-2 C38C6.2 Caenorhabditis elegans
WBGene00000254 bli-4 K04F10.4 Caenorhabditis elegans
WBGene00000387 cdc-25.2 F16B4.8 Caenorhabditis elegans
WBGene00000530 clh-3 E04F6.11 Caenorhabditis elegans
WBGene00000550 clu-1 F55H2.6 Caenorhabditis elegans
WBGene00000597 col-8 F11H8.3 Caenorhabditis elegans
WBGene00000599 col-10 B0222.8 Caenorhabditis elegans
WBGene00000601 col-12 F15H10.1 Caenorhabditis elegans
WBGene00000602 col-13 F15H10.2 Caenorhabditis elegans
WBGene00000609 col-20 F11G11.11 Caenorhabditis elegans
WBGene00000611 col-34 F36A4.10 Caenorhabditis elegans
WBGene00000620 col-43 ZC513.8 Caenorhabditis elegans
WBGene00000641 col-65 K08C9.4 Caenorhabditis elegans
WBGene00000646 H17B01.2 H17B01.2 Caenorhabditis elegans
WBGene00000653 col-77 M195.1 Caenorhabditis elegans
WBGene00000656 col-80 C09G5.5 Caenorhabditis elegans
WBGene00000667 col-92 W05B2.6 Caenorhabditis elegans
WBGene00000668 col-93 W05B2.5 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage after an hermaphrodite animal is fully-developed and reaches maturity. adult hermaphrodite Ce WBls:0000057

0 Processes

0 Regulated By Gene

1 Regulated By Molecule

Name Primary Identifier
Humic Substances WBMol:00002927