WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Cluster :

Algorithm  Intensities of spot features annotated as Bad or Not Found in the .gpr files were set to 1 to be removed from further analysis, and all of the six processed .gpr data were converted to .mev file with TIGR ExpressConverter ver. 1.7. The .mev files were processed with TIGR MIDAS ver. 2.19 with parameters set as follows: one bad channel tolerance policy as generous, with both of channel flag checked and background unchecked. The data were normalized by lowess normalization with default settings and with block and slide SD regularization. Authors then calculated log2(ASER/ASEL) ratios for each gene on the microarray. For the two pairs of dye-swapped repeats, authors calculated the mean log2(ASER/ASEL) of each repeat, so that up to four log2(ASER/ASEL) values per spot were obtained. Authors then calculated the percentile rank for each gene. Each gene spot detected more than once (18 847 spots) were subjected to MannWhitneys U test to assess whether its percentile rank values are significantly higher compared to the rest of the genes detected in the same experiments. Resulting significance levels are shown by P-values. From the P-values, false discovery rate (FDR) was further calculated by the Benjamini and Hochberg method. Statistical analyses were done by using R software version 2.9. Description  Genes that showed lower expression level in ASER than in ASEL neuron by mRNA tagging.
Primary Identifier  WBPaper00035424:ASER_down

1 Anatomy Terms

Definition Name Synonym Primary Identifier
Neuron class of two ciliated neurons that are part of the amphid sensilla; the endings are in the amphid channel, which is open to the outside ASE   WBbt:0005663

22 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001533 gcy-6 B0024.6 Caenorhabditis elegans
WBGene00001540 gcy-14 ZC412.2 Caenorhabditis elegans
WBGene00001542 gcy-17 W03F11.2 Caenorhabditis elegans
WBGene00001545 gcy-20 F21H7.9 Caenorhabditis elegans
WBGene00002115 ins-32 Y8A9A.6 Caenorhabditis elegans
WBGene00003098 lys-9 C54C8.6 Caenorhabditis elegans
WBGene00003522 nas-3 K06A4.1 Caenorhabditis elegans
WBGene00005454 srh-248 H05B21.2 Caenorhabditis elegans
WBGene00005654 srr-3 F36D3.3 Caenorhabditis elegans
WBGene00006161 str-109 F10A3.5 Caenorhabditis elegans
WBGene00006965 xtr-1 F54F7.4 Caenorhabditis elegans
WBGene00007108 gspd-1 B0035.5 Caenorhabditis elegans
WBGene00007985 swah-1 C36F7.2 Caenorhabditis elegans
WBGene00008422 ecps-1 D2045.2 Caenorhabditis elegans
WBGene00009147 F26C11.3 F26C11.3 Caenorhabditis elegans
WBGene00011453 ugt-56 T04H1.8 Caenorhabditis elegans
WBGene00015267 chin-1 BE0003N10.2 Caenorhabditis elegans
WBGene00015538 sams-3 C06E7.1 Caenorhabditis elegans
WBGene00021169 srt-40 Y5H2B.7 Caenorhabditis elegans
WBGene00015911 C17F4.3 C17F4.3 Caenorhabditis elegans
WBGene00045297 fbxc-43 C16A11.9 Caenorhabditis elegans
WBGene00007454 C08F11.7 C08F11.7 Caenorhabditis elegans

0 Life Stages

0 Processes

0 Regulated By Gene

0 Regulated By Molecule