WormMine: ExpressionCluster WBPaper00037950:A-class-motor-neurons_larva_enriched

• Algorithm: A Mann-Whitney U test with an empirical background model and FDR correction for multiple testing was used to detect expressed transcripts (Benjamini and Hochberg 1995). Genes and TARs with an FDR <= 0.05 were reported as expressed above background. Authors detected differentially expressed transcripts using a method based on linear models. Genes and TARs were called differentially expressed if the FDR was <= 0.05 and the fold change (FC) >= 2.0. To more strictly correct for potential false-positives resulting from multiple sample comparisons, authors divided individual FDR estimates by the number of samplesor sample comparisons, respectively. This resulted in an adjusted FDR of 1.3 * 0.0001 for expression above background and of 7.4 * 0.0001 for differential expression. Authors called genes selectively enriched in a given tissue if they met the following requirements: (1) enriched expression in a given tissue (FDR <= 0.05 and FC >= 2.0), (2) fold change versus reference among the upper 40% of the positive FC range observed for this gene across all tissues, and (3) fold-change entropy among the lower 40% of the distribution observed for all genes.
• Description: Genes significantly enriched (> 2x, FDR < 5%) in a particular cell-type versus a reference sample of all cells at the same stage.
• Primary Identifier: WBPaper00037950:A-class-motor-neurons_larva_enriched

2 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Neuron class of nine ventral cord motor neuron, innervates dorsal muscle.	DA neuron		WBbt:0005278
Neuron class of twelve motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VA neuron		WBbt:0005339

684 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000002	aat-1	F27C8.1	Caenorhabditis elegans
WBGene00000036	ace-2	Y44E3A.2	Caenorhabditis elegans
WBGene00000037	ace-3	Y48B6A.8	Caenorhabditis elegans
WBGene00000042	acr-2	K11G12.2	Caenorhabditis elegans
WBGene00000048	acr-9	C40C9.2	Caenorhabditis elegans
WBGene00000051	acr-12	R01E6.4	Caenorhabditis elegans
WBGene00000053	acr-14	T05C12.2	Caenorhabditis elegans
WBGene00000058	acr-19	C31H5.3	Caenorhabditis elegans
WBGene00000060	acr-21	F27B3.2	Caenorhabditis elegans
WBGene00000068	acy-1	F17C8.1	Caenorhabditis elegans
WBGene00000069	acy-2	C10F3.3	Caenorhabditis elegans
WBGene00000089	aex-6	Y87G2A.4	Caenorhabditis elegans
WBGene00000156	apr-1	K04G2.8	Caenorhabditis elegans
WBGene00000157	aps-2	F02E8.3	Caenorhabditis elegans
WBGene00000165	aps-3	Y48G8AL.14	Caenorhabditis elegans
WBGene00000166	apt-9	W04G3.4	Caenorhabditis elegans
WBGene00000192	arl-8	Y57G11C.13	Caenorhabditis elegans
WBGene00000248	ben-1	C54C6.2	Caenorhabditis elegans
WBGene00000277	cab-1	C23H4.1	Caenorhabditis elegans
WBGene00000279	cah-1	F54D8.4	Caenorhabditis elegans
WBGene00000284	cah-6	T28F2.3	Caenorhabditis elegans
WBGene00000301	cav-1	T13F2.8	Caenorhabditis elegans
WBGene00000368	ccb-1	T28F2.5	Caenorhabditis elegans
WBGene00000403	casy-1	B0034.3	Caenorhabditis elegans
WBGene00000431	ceh-6	K02B12.1	Caenorhabditis elegans
WBGene00000437	ceh-13	R13A5.5	Caenorhabditis elegans
WBGene00000460	ceh-39	T26C11.7	Caenorhabditis elegans
WBGene00000476	cfi-1	T23D8.8	Caenorhabditis elegans
WBGene00000501	cho-1	C48D1.3	Caenorhabditis elegans
WBGene00000510	cka-2	C52B9.1	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023

0 Processes

0 Regulated By Gene

0 Regulated By Molecule