WormMine: RNAi WBRNAi00107825

• WormBase ID: WBRNAi00107825
• Phenotype Remark: Figure 3, unsealed phagosomes can be labeled by PLCδ1-PH and the membrane impermeable dye FM4-64. Loss of mtm-1, piki-1, lst-4, dyn-1 or ocrl-1 shows phagosome sealing defective. "Phagosomes in mtm-1(gk890934) and mtm-1 RNAi worms were all labeled by FM4-64, Annexin V, and PLCδ1-PH, indicating defects in phagosomal sealing (Fig 3, E-F'', L, and M; and Fig S3, D-D''', H, and I)."
• Remark: mtm-1 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003475	mtm-1	Y110A7A.5	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Y110A7A.5	Y110A7A.5	1767	I: 5134767-5134806

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0002394	phagosome sealing defective	The closure of a phagosome does not occur and it remains connected with the plasma membrane, leaving the lumen open to the outside. Complete closure usually occurs once an apoptotic cell has been surrounded by an engulfing cell.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00048406

0 Strain