WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00078442 Phenotype Remark  Embryos fail to establish a central spindle, in addition ZEN-4 and AIR-2, normally found at this structure, are mislocalized.
Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000383 cdc-14 C17G10.4 Caenorhabditis elegans
WBGene00270322 C17G10.13 C17G10.13 Caenorhabditis elegans

7 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C17G10.13 C17G10.13 1161   II: 5587703-5588272
CDS:C17G10.4e C17G10.4e 2124   II: 5589593-5589616
CDS:C17G10.4d C17G10.4d 2088   II: 5589655-5589927
CDS:C17G10.4c C17G10.4c 2046   II: 5590381-5590611
CDS:C17G10.4a C17G10.4a 2082   II: 5589593-5589616
CDS:C17G10.4g C17G10.4g 2088   II: 5590381-5590611
CDS:C17G10.4h C17G10.4h 2130   II: 5589655-5589927

0 Laboratories

6 Phenotype

Identifier Name Description
WBPhenotype:0000050 embryonic lethal Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000777 polar body extrusion defective early emb Unextruded or resorbed polar body(ies) leading to an extra PNs in P0 and/or extra karyomeres in AB/P1.
WBPhenotype:0000436 protein subcellular localization variant Any variation in the placement of a protein within in a cell or cellular compartment compared to control.
WBPhenotype:0000759 spindle defective early emb Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle.
WBPhenotype:0001143 multiple nuclei early emb Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0001130 cytokinesis fails early emb Cells of the embryo attempt to divide but fail to form two daughter cells.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00005453

0 Strain