WormMine: RNAi WBRNAi00082044

• WormBase ID: WBRNAi00082044
• Phenotype Remark: A short duration of RNAi feeding leads to polarity defects (symmetric two-cell embryos) while longer durations of feeding lead to unprogressed one-cell embryos. Polarity defects further shown by localization of PAR-@ and PAR-3. RNAi caused uniform PAR-3 around the cortex and PAR-2 is mislocalized to cytoplasmic foci clustered around the microtubule asters.
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003134	mat-3	F10C5.1	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F10C5.1	F10C5.1	2022	III: 475463-475528

1 Laboratories

Primary Identifier
HY

4 Phenotype

Identifier	Name	Description
WBPhenotype:0000034	embryonic polarity variant	Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals.
WBPhenotype:0000436	protein subcellular localization variant	Any variation in the placement of a protein within in a cell or cellular compartment compared to control.
WBPhenotype:0000748	asymmetric cell division defective early emb	Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes).
WBPhenotype:0000040	one cell arrest early emb	Embryos fail to divide and arrest as one-cell embryos.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005095

0 Strain