WormMine: RNAi WBRNAi00101797

• WormBase ID: WBRNAi00101797
• Genotype: rrf-3(pk1426) II; ccIs4438 (intrinsic CC(CoelomoCyte)::gfp) III
• Phenotype Remark: Postembryonic pop-1 RNAi results in both fewer M-lineage derived coelomocytes (CC's)(in 66% of animals) and extra M-lineage derived CCs (in 13% of animals) as determined by CC::GFP. Authors report that loss of CCs was due to a combination of under-proliferation of the dorsal M lineage and fate transformation of M.d(l/r)pa to the fate of its posterior sister M.d(l/r)pp (normally fated to become body wall muscles (BWMs)).
• Remark: (Table 2) pop-1 RNAi-P (postembryonic RNAi). Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004077	pop-1	W10C8.2	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:W10C8.2	W10C8.2	1317	I: 2823468-2823937

1 Laboratories

Primary Identifier
LW

6 Phenotype

Identifier	Name	Description
WBPhenotype:0000095	M lineage variant	The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage.
WBPhenotype:0000961	pattern of transgene expression variant	Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000414	cell fate transformation	The cell takes on a different identity from which it was initially committed.
WBPhenotype:0001912	fewer coelomocytes	The number of coelomocytes are reduced compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds.
WBPhenotype:0000173	cell proliferation reduced	The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased.
WBPhenotype:0001913	excess coelomocytes	The number of coelomocytes are increased compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00033137

0 Strain