WormMine: RNAi WBRNAi00092400

• WormBase ID: WBRNAi00092400
• Genotype: Pdat-1::GFP; rrf-3(pk1426)
• Phenotype Remark: skn-1 RNAi slightly (but significantly) enhanced the dopaminergic neuron degeneration induced by the presence of 100 micromolar Aluminum (Al3+), implicating SKN-1 in a neuroprotective role in Aluminum-induced dopaminergic neuron degeneration.
• Remark: (Figure 6a) skn-1 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004804	skn-1	T19E7.2	Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:T19E7.2d	T19E7.2d	672	IV: 5651764-5651840
CDS:T19E7.2c	T19E7.2c	1602	IV: 5651764-5651840
CDS:T19E7.2a	T19E7.2a	1872	IV: 5651764-5651840
CDS:T19E7.2b	T19E7.2b	933	IV: 5651764-5651840

1 Laboratories

Primary Identifier
RJ

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000591	metal response variant	Animals exhibit variations in their response to a specific metal compared to that observed in control animals.
WBPhenotype:0000636	neuron degeneration variant	Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00041701

0 Strain