WormMine: RNAi WBRNAi00092401

• WormBase ID: WBRNAi00092401
• Genotype: Pdat-1::GFP; rrf-3(pk1426)
• Phenotype Remark: ced-4 RNAi partially suppressed the dopaminergic neuron degeneration induced by the presence of 100 micromolar Aluminum (Al3+), implicating apoptosis in the process
• Remark: (Figure 6b) ced-4 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000418	ced-4	C35D10.9	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C35D10.9a	C35D10.9a	1650	III: 4852325-4852775
CDS:C35D10.9b	C35D10.9b	1716	III: 4852325-4852775

1 Laboratories

Primary Identifier
RJ

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000591	metal response variant	Animals exhibit variations in their response to a specific metal compared to that observed in control animals.
WBPhenotype:0000636	neuron degeneration variant	Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00041701

0 Strain