WormMine: RNAi WBRNAi00008154

• WormBase ID: WBRNAi00008154
• Phenotype Remark: Observed in >=10% of progeny.
• Remark: PCR product used to make dsRNA was amplified from genomic DNA.
• Secondary Identifier: PF:GL1_7F2

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00022852	ZK1127.5	ZK1127.5	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:ZK1127.5	ZK1127.5	1140	II: 7050675-7050804

1 Laboratories

Primary Identifier
KK

17 Phenotype

Identifier	Name	Description
WBPhenotype:0000697	protruding vulva	Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva.
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000031	slow growth	Any variation that causes a reduction in growth rate compared to control.
WBPhenotype:0000583	dumpy	Worms are shorter and stouter than control animals at the same developmental stage.
WBPhenotype:0000640	egg laying variant	Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control.
WBPhenotype:0001168	pseudocleavage absent early emb	No pseudocleavage is observed before or during pronuclear migration.
WBPhenotype:0000059	larval arrest	The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
WBPhenotype:0001037	sterile progeny	Any variation that compromises the reproductive ability of the progeny of an animal.
WBPhenotype:0001155	pronuclei meet centrally early emb	The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
WBPhenotype:0001105	P0 spindle position abnormal	Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal.
WBPhenotype:0001119	cell cycle slow early emb	Embryos take longer to divide during the first and second cell divisions.
WBPhenotype:0001143	multiple nuclei early emb	Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0001130	cytokinesis fails early emb	Cells of the embryo attempt to divide but fail to form two daughter cells.
WBPhenotype:0002501	ectopic cleavage furrow early emb	One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WBPhenotype:0001109	P0 spindle rotation delayed early emb	P0 spindle rotates late in the inviable one- to four-cell embryo.
WBPhenotype:0001080	excessive blebbing early emb	Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
WBPhenotype:0001108	P0 spindle rotation failure early emb	P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001