WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00007724 Phenotype Remark  Observed in <10% of progeny.
Remark  PCR product used to make dsRNA was amplified from genomic DNA. Secondary Identifier  PF:GL1_3A1

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003150 mbk-2 F49E11.1 Caenorhabditis elegans

14 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F49E11.1h F49E11.1h 1608   IV: 13024534-13024618
CDS:F49E11.1e F49E11.1e 1506   IV: 13026421-13026448
CDS:F49E11.1f F49E11.1f 1518   IV: 13027264-13027303
CDS:F49E11.1i F49E11.1i 1572   IV: 13031334-13031382
CDS:F49E11.1d F49E11.1d 1428   IV: 13031644-13031768
CDS:F49E11.1j F49E11.1j 1473   IV: 13031644-13031768
CDS:F49E11.1n F49E11.1n 1410   IV: 13031644-13031768
CDS:F49E11.1a F49E11.1a 1527   IV: 13031334-13031382
CDS:F49E11.1b F49E11.1b 2454   IV: 13009158-13009229
CDS:F49E11.1c F49E11.1c 2391   IV: 13009158-13009229
CDS:F49E11.1g F49E11.1g 2403   IV: 13009158-13009229
CDS:F49E11.1k F49E11.1k 2340   IV: 13009158-13009229
CDS:F49E11.1l F49E11.1l 1545   IV: 13024534-13024618
CDS:F49E11.1m F49E11.1m 1509   IV: 13031334-13031382

1 Laboratories

Primary Identifier
KK

15 Phenotype

Identifier Name Description
WBPhenotype:0000050 embryonic lethal Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000583 dumpy Worms are shorter and stouter than control animals at the same developmental stage.
WBPhenotype:0000038 exploded through vulva The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture.
WBPhenotype:0001037 sterile progeny Any variation that compromises the reproductive ability of the progeny of an animal.
WBPhenotype:0001106 spindle orientation variant AB or P1 early emb The orientation of the spindle is aberrant in either the AB or the P1 cell.
WBPhenotype:0001169 pseudocleavage exaggerated early emb Embryos have more pronounced pseudocleavage than normal.
WBPhenotype:0001143 multiple nuclei early emb Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0001130 cytokinesis fails early emb Cells of the embryo attempt to divide but fail to form two daughter cells.
WBPhenotype:0002501 ectopic cleavage furrow early emb One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WBPhenotype:0001080 excessive blebbing early emb Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos.
WBPhenotype:0001158 pronuclear breakdown asynchronous early emb Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo.
WBPhenotype:0001131 loose mitotic furrow early emb Once formed, the mitotic furrow can "slide"laterally.
WBPhenotype:0001126 cell cell contacts abnormal in four cell embryo Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos.
WBPhenotype:0001127 EMS anterior extension fails early emb The EMS blastomere fails to extend anteriorly and make extensive contact (hug) with the ABa blastomere.
WBPhenotype:0001108 P0 spindle rotation failure early emb P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001