WormMine: RNAi WBRNAi00106297

• WormBase ID: WBRNAi00106297
• Phenotype Remark: "To understand the role of dpy-21 in the DCC, we compared gene expression changes in dpy-27 RNAi, dpy-21(e428), set-1(tm1821) and set-4(n4600) mutant L3 larvae by clustering differential expression ratios on the X chromosome and autosomes (Fig 6A). We note that while the effect of dpy-27 RNAi and dpy-21(e428) were generally similar on the X, genes in several clusters were affected differently between dpy-27 RNAi and dpy-21 (e428). We performed gene ontology (GO) analyses comparing enriched functions in each cluster compared to the whole genome (Fig 6B). Interestingly, the effect of dpy-27 RNAi and dpy-21(e428) on clusters enriched for cuticle genes were opposite, yet both mutations result in a dumpy phenotype."
• Remark: dpy-27 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001086	dpy-27	R13G10.1	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R13G10.1	R13G10.1	4410	III: 3813909-3814171

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000583	dumpy	Worms are shorter and stouter than control animals at the same developmental stage.
WBPhenotype:0000718	dosage compensation variant	Variations in the process of normalizing the expression level of X-linked genes between XX and XO animals compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00048953

0 Strain