WormMine: RNAi WBRNAi00106398

• WormBase ID: WBRNAi00106398
• Genotype: unc-45(m94)
• Phenotype Remark: "Given that genetic background variations can confound the interpretation of genetic interactions, the three genes that affected unc-45(e286) were tested for their effects on animals carrying the unc-45(m94) allele (Figure 2A). Age-synchronized L1 unc45(m94) mutant worms maintained under permissive conditions were treated with RNAi for CeHsp90, CeHop or CeAha1 and compared to animals that took up the empty vector control. Similar to the e286 allele, unc-45(m94) animals treated by RNAi for CeHsp90, CeHop, or CeAha1 were completely paralyzed on day 2 of adulthood under permissive conditions (Figures 2B,C). Although CeAha1 or CeHop RNAi treatment reduced the levels of the corresponding proteins to a similar extent in all strains examined, CeHop and CeAha1 RNAi only induced paralysis in unc-45(ts)-expressing animals (Figures 2B,C and Figure S3)."
• Remark: (Figure 2) sti-1/CeHop RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. If Ahringer clone not available, Vidal laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00019983	sti-1	R09E12.3	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R09E12.3	R09E12.3	963	V: 773591-773602

0 Laboratories

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000644	paralyzed	Animals do not move and are not responsive to external mechanical stimulation.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00046852

0 Strain