WormMine: RNAi WBRNAi00106287

• WormBase ID: WBRNAi00106287
• Genotype: CeAha1/C01G10.8(ok3501)
• Phenotype Remark: "When CeAha1(ok3501) knockout animals were treated with CeHsp90(RNAi), only 13.9 7% of the animals were motile by the first day of egg-laying, while no effect on motility was observed for CeAha1(ok3501) animals grown on the empty vector control (Figures 5A,B). This was specific to CeAha1(ok3501) animals, as most of the wild-type animals treated with CeHsp90 RNAi were motile (76.6 4%) (Figure 5B). Moreover, both wildtype and CeAha1(ok3501) animals treated with CeHsp90(RNAi) showed a complete larval arrest phenotype (Figure 5A)."
• Remark: (Figure 5) daf-21/CeHsp90 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. If Ahringer clone not available, Vidal laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000915	hsp-90	C47E8.5	Caenorhabditis elegans
WBGene00044180	C47E8.11	C47E8.11	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C47E8.5	C47E8.5	2109	V: 14686164-14686313
CDS:C47E8.11	C47E8.11	237	V: 14688637-14688711

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000644	paralyzed	Animals do not move and are not responsive to external mechanical stimulation.
WBPhenotype:0000059	larval arrest	The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00046852

0 Strain