WormMine: RNAi WBRNAi00082083

• WormBase ID: WBRNAi00082083
• Genotype: dat-1::gfp; rrf-3(pk1426)
• Phenotype Remark: Worms exhibited resistance to Mn2+(manganese ion)-induced dopamine neuronal degradation after RNAi of smf-1

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004876	smf-1	K11G12.4	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:K11G12.4a	K11G12.4a	1689	X: 6719800-6719943

1 Laboratories

Primary Identifier
RJ

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001904	manganese toxicity resistant	Animals fail to exhibit toxicity to the concentration of manganese that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to manganese include dopamine (DA) neuron neurodegeneration.
WBPhenotype:0000636	neuron degeneration variant	Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00035259

0 Strain