WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00092704 Phenotype Remark  unc-94(RNAi) embryos exhibit clumps of circumferential actin filament bundles (CFBs), clumping of junctional actin, and an overall decrease in the amount of actin present in seam cells. Muscle organization is also perturbed.
Remark  (Figure S2C, S2D) unc-94 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006823 unc-94 C06A5.7 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C06A5.7a C06A5.7a 1179   I: 5993301-5993338
CDS:C06A5.7b C06A5.7b 1206   I: 5993301-5993338

1 Laboratories

Primary Identifier
SU

3 Phenotype

Identifier Name Description
WBPhenotype:0000603 muscle system morphology variant Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work.
WBPhenotype:0001354 actin cytoskeleton filament morphology phenotype Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).
WBPhenotype:0002124 circumferential actin bundles disorganized The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041277

0 Strain