WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00088793 Phenotype Remark  paa-1(RNAi) produces defects in chromosome alignment, cell cycle progression, and mitotic exit.
Remark  paa-1 RNAi

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003901 paa-1 F48E8.5 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F48E8.5 F48E8.5 1773   III: 5450741-5451249

1 Laboratories

Primary Identifier
OC

8 Phenotype

Identifier Name Description
WBPhenotype:0000318 cell cycle delayed Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells.
WBPhenotype:0000746 cell division variant Any variation that alters the physical partitioning and separation of a cell into daughter cells compared to control.
WBPhenotype:0001139 nuclear envelope assembly variant early emb Nuclear envelope does not reassemble properly.
WBPhenotype:0001903 centrosome biogenesis variant Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression.
WBPhenotype:0002062 chromosome decondensation failure The process of decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form is abolished.
WBPhenotype:0001102 mitotic spindle defective early emb Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a mitotic cell cycle.
WBPhenotype:0001584 chromosome alignment variant Any variation in the movement of chromosomes to the spindle equator during mitosis compared to control animals.
WBPhenotype:0001876 centriole biogenesis variant Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038325

0 Strain