WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00092703 Genotype  hmp-1(fe4); jcIs24 [jac-1p::GFP]
Phenotype Remark  Seam-dorsal and seam-ventral epidermal-cell borders in hmp-1(fe4);unc-94(RNAi) embryos were highly disrupted, appearing ripped apart and yielding a characteristic zigzag pattern. JAC-1::GFP is fragmented and mislocalized at seam-dorsal and seam-ventral borders and actin is depleted in areas of disrupted JAC-1::GFP, as determined by phalloidin staining and JAC-1::GFP fluorescence. Remark  (Figure 2A, 3, S3D, Table S1) unc-94 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006823 unc-94 C06A5.7 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C06A5.7a C06A5.7a 1179   I: 5993301-5993338
CDS:C06A5.7b C06A5.7b 1206   I: 5993301-5993338

1 Laboratories

Primary Identifier
SU

4 Phenotype

Identifier Name Description
WBPhenotype:0001587 actin organization biogenesis phenotype Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001403 antibody subcellular localization variant Any variation in the placement of a protein, as detected by antibody staining, within in a cell or cellular compartment compared to control.
WBPhenotype:0001658 intercellular junction variant Animals exhibit variations in the specialized region of connection between two cells compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041277

0 Strain