WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085581 Phenotype Remark 
Remark 

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00020868 eif-1 T27F7.3 Caenorhabditis elegans
WBGene00194986 pigb-1 T27F7.4 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T27F7.3 T27F7.3 330   II: 4991054-4991098
CDS:T27F7.4 T27F7.4 1491   II: 4991587-4993077

1 Laboratories

Primary Identifier
OD

19 Phenotype

Identifier Name Description
WBPhenotype:0001260 oocyte morphology variant Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control.
WBPhenotype:0001355 gonad morphology variant Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas).
WBPhenotype:0001951 pachytene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas).
WBPhenotype:0000690 gonad migration variant Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas).
WBPhenotype:0001980 germ cell compartment expansion variant Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes).
WBPhenotype:0001972 germ cell compartment multinucleate Germ cell compartments contain multiple nuclei.
WBPhenotype:0000182 apoptosis reduced Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0001952 germline nuclear positioning variant Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control.
WBPhenotype:0001982 cell membrane organization biogenesis variant Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
WBPhenotype:0001944 oocyte number decreased A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control.
WBPhenotype:0001945 oocytes small The size of haploid female germ cells (oocytes) are significantly smaller compared to control.
WBPhenotype:0001940 rachis morphology variant Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis.
WBPhenotype:0001969 germ cell compartment morphology variant Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis). These compartments eventually undergo cellularization and become oocytes.
WBPhenotype:0001979 gonad vesiculated Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad.
WBPhenotype:0001950 diplotene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file.
WBPhenotype:0001953 nuclear fallout Nuclei have fallen out of developing germ cell compartments into the rachis.
WBPhenotype:0001958 gonad degenerate Animals contain a gonad that initially functioned, but subsequently stopped. In hermaphrodites or females there is often the presence old embryos and/or hatched larva, but no young embryos, in the uterus.
WBPhenotype:0001941 rachis narrow The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals.
WBPhenotype:0001949 diakinesis region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diakinesis stage. In C. elegans the diakinesis region occurs in the proximal gonad arm and is preceded by the diplotene region. In the diakinesis region oocytes arrest until oocyte maturation occurs.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038381

1 Strain

WormBase ID
WBStrain00029219