WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00097409 Phenotype Remark  ifg-1 RNAi using construct C2 resulted in no embryos nor any evidence of unfertilized oocytes in the uterus. C2 (RNAi) resulted in two populations of worms. In one population, body size and gonad development was consistent with the larval L2 stage. The other population contained an extended U-shaped gonad consistent with an adult germline despite the small L3-like body size. All ifg-1(RNAi) worms displayed marked deterioration in the proximal gonad.
Remark  (Figure 4b, 4c) ifg-1 RNAi (construct C2)
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002066 ifg-1 M110.4 Caenorhabditis elegans

5 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:M110.4b M110.4b 3468   II: 8217254-8217302
CDS:M110.4d M110.4d 3480   II: 8217254-8217302
CDS:M110.4e M110.4e 3483   II: 8217254-8217302
CDS:M110.4a M110.4a 3471   II: 8217254-8217302
CDS:M110.4c M110.4c 3129   II: 8217839-8218837

1 Laboratories

Primary Identifier
KX

5 Phenotype

Identifier Name Description
WBPhenotype:0000154 reduced brood size The characteristic number of offspring produced is lower compared to that of control animals.
WBPhenotype:0000050 embryonic lethal Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000691 gonad development variant Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control.
WBPhenotype:0000229 small Animals are shorter and thinner than control animals at the same developmental stage.
WBPhenotype:0001958 gonad degenerate Animals contain a gonad that initially functioned, but subsequently stopped. In hermaphrodites or females there is often the presence old embryos and/or hatched larva, but no young embryos, in the uterus.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00031847

0 Strain