WormMine: RNAi WBRNAi00088831

• WormBase ID: WBRNAi00088831
• Genotype: [DYN-1::GFP]
• Phenotype Remark: In rack-1(RNAi) embryos, the initial anterior enrichment of DYN-1-GFP foci during establishment phase was not affected (Fig. 3E; also see Video S6). However, during maintenance phase bright DYN-1-GFP puncta expanded into the posterior cortex (Fig. 3F, 7/12 embryos), and sometimes shrunk to a smaller size than that of wild type (2/12 embryos). The expansion/shrinkage was corrected with furrow initiation, and the cleavage furrow was properly placed (Fig. 3G). DYN-1 localization in the two daughter cells was normal, with the exception that in embryos with failed cytokinesis DYN-1-GFP expanded to the posterior cortex after furrow regression (Fig. 3H). We also noticed that in rack-1(RNAi) embryos, the DYN-1-GFP foci were clumping into larger foci than in wild type.
• Remark: rack-1 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00010556	rack-1	K04D7.1	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:K04D7.1	K04D7.1	978	IV: 10176710-10176824

1 Laboratories

Primary Identifier
MAD

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000679	transgene subcellular localization variant	Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00038375

0 Strain