WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00088835 Genotype  [GFP::TBB-2; GFP::PAR-2; mCherry::PAR-6]
Phenotype Remark  In zyg-9(RNAi) embryos, polarity establishment was not affected, but during maintenance phase the boundaries between PAR-6 and PAR-2 were not perpendicular to the AP axis (Fig. 4M-O and 5F; also see Video S11). Remark  zyg-9(RNAi)

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006994 zyg-9 F22B5.7 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F22B5.7 F22B5.7 4248   II: 8457821-8458012

1 Laboratories

Primary Identifier
MAD

8 Phenotype

Identifier Name Description
WBPhenotype:0001152 pronuclear migration defective early emb Pronucleus migration is abnormal in the inviable embryo.
WBPhenotype:0000034 embryonic polarity variant Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals.
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001588 microtubule organization biogenesis variant Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas).
WBPhenotype:0000766 centrosome pair and associated pronuclear rotation variant Any variation in the rotation of the centrosome-pronuclear complex after its migration toward the center of the embryo, compared to control.
WBPhenotype:0000761 spindle position orientation defective early emb Early embryos exhibit defects in the placement or the alignment of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis.
WBPhenotype:0002501 ectopic cleavage furrow early emb One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells.
WBPhenotype:0001158 pronuclear breakdown asynchronous early emb Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038375

0 Strain