WormMine: RNAi WBRNAi00097840

• WormBase ID: WBRNAi00097840
• Genotype: opEx1314 [Pced-1::YFP::RAB-5]
• Phenotype Remark: RNAi resulted in an accumulation of YFP::RAB-5 halos in phagosomes engulfing apoptotic cell corpses, suggesting a defect/arrest in phagosome maturation at the RAB-5(+) stage
• Remark: (Figure 2k, Table S1d) rab-7 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

2 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004271	rab-7	W03C9.3	Caenorhabditis elegans
WBGene00012221	W03C9.5	W03C9.5	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:W03C9.3	W03C9.3	630	II: 11965655-11965741

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000679	transgene subcellular localization variant	Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001846	phagosome maturation defective	Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00036059

0 Strain