WormMine: RNAi WBRNAi00098315

• WormBase ID: WBRNAi00098315
• Genotype: Pced-1::2xFYVE::GFP (marker for phosphatidylinositol 3-phosphate (PtdIns(3)P) in apoptotic corpse-engulfing cells)
• Phenotype Remark: rab-5 RNAi resulted in a reduced percentage of gonadal phagosomes labeled with 2xFYVE::GFP (a marker for phosphatidylinositol 3-phosphate (PtdIns(3)P)) and an accumulation of germ cell corpses
• Remark: (Figure 4E, S4) rab-5 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004268	rab-5	F26H9.6	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F26H9.6	F26H9.6	627	I: 9308445-9308535

1 Laboratories

Primary Identifier
ZH

3 Phenotype

Identifier	Name	Description
WBPhenotype:0000679	transgene subcellular localization variant	Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001180	accumulated germline cell corpses	Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed.
WBPhenotype:0001846	phagosome maturation defective	Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00040691

0 Strain