WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00090833 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  GFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated Remark  (Table S1) F55G1.10/his-61 RNAi

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

5 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001907 his-33 F17E9.13 Caenorhabditis elegans
WBGene00001921 his-47 B0035.7 Caenorhabditis elegans
WBGene00001931 his-57 F54E12.5 Caenorhabditis elegans
WBGene00001935 his-61 F55G1.10 Caenorhabditis elegans
WBGene00001939 his-65 H02I12.7 Caenorhabditis elegans

7 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:B0035.7 B0035.7 384   IV: 11324056-11324439
CDS:F54E12.5b F54E12.5b 444   IV: 11340412-11340791
CDS:F54E12.5c F54E12.5c 411   IV: 11340412-11340791
CDS:F17E9.13 F17E9.13 384   IV: 8335335-8335718
CDS:F54E12.5a F54E12.5a 384   IV: 11340412-11340795
CDS:F55G1.10 F55G1.10 384   IV: 7485834-7486217
CDS:H02I12.7 H02I12.7 384   IV: 11401092-11401475

1 Laboratories

Primary Identifier
MZE

3 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094 RAB-11 recycling endosome morphology variant Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002095 lysosome-related organelle morphology variant Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain