WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085635 Phenotype Remark 
Remark 

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00007686 tomm-40 C18E9.6 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C18E9.6 C18E9.6 906   II: 8972375-8972498

1 Laboratories

Primary Identifier
OD

13 Phenotype

Identifier Name Description
WBPhenotype:0001260 oocyte morphology variant Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control.
WBPhenotype:0000730 apoptosis variant Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell.
WBPhenotype:0001951 pachytene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas).
WBPhenotype:0001980 germ cell compartment expansion variant Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes).
WBPhenotype:0001180 accumulated germline cell corpses Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed.
WBPhenotype:0001982 cell membrane organization biogenesis variant Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
WBPhenotype:0001944 oocyte number decreased A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control.
WBPhenotype:0001971 germ cell compartment anucleate Germ cell compartments do not contain a nucleus.
WBPhenotype:0001979 gonad vesiculated Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad.
WBPhenotype:0001950 diplotene region organization variant Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file.
WBPhenotype:0001955 multiple nuclei oocyte Haploid female germ cells (oocytes) contain more than one nucleus.
WBPhenotype:0001956 oocytes lack nucleus Haploid female germ cells (oocytes) lack a nucleus.
WBPhenotype:0001941 rachis narrow The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038381

1 Strain

WormBase ID
WBStrain00029219