WormMine: RNAi WBRNAi00091437

• WormBase ID: WBRNAi00091437
• Phenotype Remark: tat-5 RNAi resulted in enlarged lysosomes compared to controls
• Remark: (Figure S5) tat-5 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00009498	tat-5	F36H2.1	Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F36H2.1a	F36H2.1a	3225	I: 9234678-9234866
CDS:F36H2.1c	F36H2.1c	3216	I: 9234678-9234866
CDS:F36H2.1d	F36H2.1d	3180	I: 9234678-9234866
CDS:F36H2.1b	F36H2.1b	3171	I: 9234678-9234866

1 Laboratories

Primary Identifier
FT

1 Phenotype

Identifier	Name	Description
WBPhenotype:0002097	lysosome morphology variant	Any variation in the form or composition of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control.

6 Phenotype _ Not _ Observed

Identifier	Name	Description
WBPhenotype:0001421	endocytic transport variant	Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control.
WBPhenotype:0000724	protein secretion variant	Variations in the regulated release of proteins from a cell or group of cells compared to control.
WBPhenotype:0002106	early endosome localization variant	Any variation in the subcellular localization of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control.
WBPhenotype:0002101	endoplasmic reticulum localization variant	Any variation in the subcellular localization of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that exists in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
WBPhenotype:0002102	golgi apparatus localization variant	Any variation in the subcellular localization of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control.
WBPhenotype:0002105	late endosome localization variant	Any variation in the subcellular localization of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control.

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00040428

0 Strain