WormMine: RNAi WBRNAi00114839

• WormBase ID: WBRNAi00114839
• Phenotype Remark: Depletion of ERM-1 causes lumenal constrictions and obstructions in the intestine. Morphological examinations of ERM-1-depleted larvae in comparison to WT larvae revealed an abnormal gut lumen of pearl string shape featuring multiple obstructions.
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation. Authors did state they used the following clones to create transcribe dsRNAs for this experiment: yk129b2, yk257f5.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001333	erm-1	C01G8.5	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C01G8.5a	C01G8.5a	1692	I: 5284598-5284690
CDS:C01G8.5b	C01G8.5b	1695	I: 5284598-5284690

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000710	intestinal morphology variant	Animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion (Wormatlas).
WBPhenotype:0001630	gut obstructed	Any variation in the developmental progression of the intestine that leads to a blockage in the alimentary canal.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00024261

0 Strain