WormMine: RNAi WBRNAi00097371

• WormBase ID: WBRNAi00097371
• Phenotype Remark: RNAi results in a decreased number of apoptotic bodies in the "apoptotic zone" of the germ line after irradiation compared to wild type, suggesting that germ cells are allowed to proliferate even in the presence of DNA damage.
• Remark: (Figure 1E) C25A1.6 RNAi

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

3 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00007707	fath-1	C25A1.5	Caenorhabditis elegans
WBGene00007708	nola-3	C25A1.6	Caenorhabditis elegans
WBGene00077526	C25A1.16	C25A1.16	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:C25A1.6	C25A1.6	195	I: 10179042-10179236
CDS:C25A1.16a	C25A1.16a	312	I: 10179238-10179318

1 Laboratories

Primary Identifier
XF

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000184	apoptosis fails to occur	Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes.
WBPhenotype:0000712	germ cell ionizing radiation response variant	Germ cells exhibit variations in their response to ionizing radiation compared to that observed in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00027740

0 Strain