WormMine: RNAi WBRNAi00077986

• WormBase ID: WBRNAi00077986
• Phenotype Remark: Seam cells fail to differentiate properly. Authors used various markers to observe the expression of seam specific NR genes. Expression of three NR reporters, nhr-75 ::GFP, nhr-81 ::GFP,and NHR-82::GFP, was undetectable in all elt-5(RNAi) embryos examined. In contrast, expression of two NR reporters, nhr-73 ::GFP and nhr-74 ::GFP, was only slightly affected, both in terms of the fraction of expressing animals and the level of GFP signal.. The remaining three NR reporters, nhr-72 ::GFP, nhr-77 ::GFP, and nhr-89 ::GFP, gave intermediate results; these were expressed much less frequently in elt-5(RNAi) embryos than in wild-type embryos, and expression was barely detectable in only a few cells for those embryos showing any expression.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001186	egl-18	F55A8.1	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F55A8.1a	F55A8.1a	1131	IV: 1913472-1913597
CDS:F55A8.1b	F55A8.1b	1140	IV: 1913472-1913597

1 Laboratories

Primary Identifier
JR

1 Phenotype

Identifier	Name	Description
WBPhenotype:0000811	epithelial cell development variant	Any variation in the progression of an epithelial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00004833

0 Strain