WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00114512 Phenotype Remark  We found that RNAi knockdown of atfs-1 could effectively suppress the increase in HSP-6:GFP induced by DMT (100 g/L). hsp-6 is a marker for mitochondrial (mt) UPR in nematodes.
Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation (ZC376.7a.1).
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00013878 atfs-1 ZC376.7 Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:ZC376.7b ZC376.7b 1419   V: 14194483-14194578
CDS:ZC376.7d ZC376.7d 846   V: 14196345-14196419
CDS:ZC376.7a ZC376.7a 1467   V: 14194483-14194578
CDS:ZC376.7c ZC376.7c 1425   V: 14194483-14194578

0 Laboratories

2 Phenotype

Identifier Name Description
WBPhenotype:0000962 level of transgene expression variant Any variation in the measured expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001719 unfolded protein response variant Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00058828

0 Strain