WormMine: RNAi WBRNAi00111046

• WormBase ID: WBRNAi00111046
• Genotype: rhIs2[pat-3::HA::gfp] I; eri-1(mg366)
• Phenotype Remark: Although RNAi against cyk-1, starting treatment on L1 larvae, results in thin body-wall muscle cells, body immobility in the middle/posterior, and protruding vulvas (Pvl) in young adults. Continued RNAi against cyk-1 in adults results in low penetrance of disruption of body-wall muscle cell contractile lattices. Simultaneous RNAi against inft-1 and/or inft-2 does not affect the penetrance of this late onset phenotype. fhod-1(tm2363) does not affect the penetrance of this late onset phenotype.
• Remark: Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000872	cyk-1	F11H8.4	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:F11H8.4a	F11H8.4a	4308	III: 7023838-7024005
CDS:F11H8.4b	F11H8.4b	4314	III: 7023838-7024005

0 Laboratories

2 Phenotype

Identifier	Name	Description
WBPhenotype:0000926	body wall muscle morphology variant	Any variation in the morphological appearance of the body wall muscle compared to control animals.
WBPhenotype:0001570	body wall muscle actin organization defective	The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00041258

0 Strain