WormMine: RNAi WBRNAi00084901

• WormBase ID: WBRNAi00084901
• Phenotype Remark: In embryos treated with cls-2 RNAi, no chromosome mass separation or assembly of anaphase microtubule bundles was observed during meiosis I or meiosis II, and consistent with the severe anaphase I defect, no polar body was formed and 12 univalent chromosomes were present during meiosis II. cls-2 RNAi led to severe pre-anaphase spindle defects

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000549	cls-2	R107.6	Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R107.6a	R107.6a	3063	III: 9055052-9055144
CDS:R107.6b	R107.6b	3072	III: 9055052-9055144

0 Laboratories

4 Phenotype

Identifier	Name	Description
WBPhenotype:0002013	univalent meiotic chromosomes	Chromosomes fails to pair with homologous chromosomes during the prophase stage of meiosis.
WBPhenotype:0001499	meiotic chromosome segregation variant	Variations in the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle, compared to control.
WBPhenotype:0000372	no polar body formation	Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas).
WBPhenotype:0001868	meiotic spindle defective	Cells undergoing meiosis exhibit defects in the overall function or activity of the meiotic spindle.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00037073

0 Strain