WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00110052 Genotype  sgk-1(ok538)
Phenotype Remark  "Specifically we investigated the interaction with age-1, akt-1, akt-2 and sgk-1 encoding kinases. Intriguingly, we uncovered that phb-1 and phb-2 RNAi resulted in lifespan extension only in the sgk-1(ok538) mutant background (Figure 1A and Table S1), recapitulating the phenotype observed in daf-2 mutants." Remark  (Table S1, Figure 1A,1C) phb-1 RNAi. Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004014 phb-1 Y37E3.9 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Y37E3.9 Y37E3.9 828   I: 2071353-2071754

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000061 extended life span The duration of viability in the adult phase of the life-cycle surpasses that of control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00045812

0 Strain