WormMine: RNAi WBRNAi00065158

• WormBase ID: WBRNAi00065158
• Genotype: pha-4(zu225)
• Phenotype Remark: Enhancement of pha-4(zu225) L1 lethality and RNAi in this background causes a pharynx unattached (pun) phenotype.
• Remark: pha-4(zu225) is a temperature sensitive allele and 24 C is a permissive temperature. The enhancement of pha-4 lethality was shown to have some specificity as no enhancement was seen in either the hsf-1(sy441), tbx-2(ut180) or lin-26(n156) backgrounds. In addiition this RNAi did not enhance the movement defect in the unc-54(r293ts) allele. Like pha-4(zu225), RNA derived from unc-54(r293) is subject to degradation by the nonsense-mediated decay pathway.

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00019947	htz-1	R08C7.3	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:R08C7.3	R08C7.3	423	IV: 4446236-4446405

1 Laboratories

Primary Identifier
SM

2 Phenotype

Identifier	Name	Description
WBPhenotype:0001748	pharynx unattached	The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity.
WBPhenotype:0000062	lethal	Animals die prematurely at any stage of the life cycle.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00028549

0 Strain