WormMine: RNAi WBRNAi00007666

• WormBase ID: WBRNAi00007666
• Phenotype Remark: Observed in >=10% of progeny.
• Remark: PCR product used to make dsRNA was amplified from genomic DNA.
• Secondary Identifier: PF:GL1_2D1

1 Organism

• Name: Caenorhabditis elegans
• Taxon Id: 6239

1 Data Sets

• WormBaseAcedbConverter

1 Inhibits Gene

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00020687	ruvb-2	T22D1.10	Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:T22D1.10	T22D1.10	1347	IV: 6917281-6917497

1 Laboratories

Primary Identifier
KK

13 Phenotype

Identifier	Name	Description
WBPhenotype:0000050	embryonic lethal	Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
WBPhenotype:0000031	slow growth	Any variation that causes a reduction in growth rate compared to control.
WBPhenotype:0000032	sick	Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc.
WBPhenotype:0000059	larval arrest	The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage.
WBPhenotype:0001037	sterile progeny	Any variation that compromises the reproductive ability of the progeny of an animal.
WBPhenotype:0001106	spindle orientation variant AB or P1 early emb	The orientation of the spindle is aberrant in either the AB or the P1 cell.
WBPhenotype:0001155	pronuclei meet centrally early emb	The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo.
WBPhenotype:0001143	multiple nuclei early emb	Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo.
WBPhenotype:0001130	cytokinesis fails early emb	Cells of the embryo attempt to divide but fail to form two daughter cells.
WBPhenotype:0001083	multiple cytoplasmic cavities early emb	Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis.
WBPhenotype:0001150	polar body reabsorbed one two early emb	A polar body is reabsorbed in either the one cell- or the two-cell embryo.
WBPhenotype:0001147	polar body defective early emb	Polar bodies are abnormal in the inviable one- to four-cell embryo.
WBPhenotype:0001113	P1 aster defective early emb	Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the P1 cell.

0 Phenotype _ Not _ Observed

1 Reference

First Author	Title	Year	Journal	Volume	Pages	PubMed ID
						WBPaper00005599

1 Strain

WormBase ID
WBStrain00000001